1901

The federal government’s first physical science research laboratory was chartered by Congress on March 3, 1901, as the National Bureau of Standards, which became the National Institute of Standards and Technology in 1988. Recognizing the critical importance of chemical measures and standards, NIST established the Chemistry Division as one of its first programs.

The steel dome stretches 200 feet in diameter and rises 100 feet at its top. To accommodate thermal expansion, the inverted bowl-shaped structure originally rested on rollers that sat on the flat tops of six-story columns

There was a time when Americans from the Eastern seaboard braved long rail trips to southern Indiana in hopes that the water at the French Lick natural mineral springs could bring relief from alcoholism, pimples, gallstones and a host of other ailments and illnesses.

Philadelphia City Hall was the largest masonry load-bearing wall building in the world at the time of its completion in 1901, stood as the tallest occupied building in the United States until 1909, and still is the largest city hall in the United States. The building covers 14.26 acres, originally contained 634 rooms with over 1 million square feet of space, and with its tower and statue of William Penn rises a total of 548 feet above the ground. The construction of Philadelphia City Hall began in 1872 and was completed in 1901.

This is the oldest operating vessel with a diagonal, compound steam engine, with disc valve gear. Operating at a higher pressure than the oscillating-cylinder engines then used in lake steamers, this type of engine was more powerful and efficient, as well as smaller. The compound engine, built by Sulzer brothers of Winterthur, uses super-heated steam from the boilers in two stages-high and low pressure-before exhausting it into a condenser. The engine produces 650 horsepower, turning two paddle wheels.

For more than a century, scientists at Rockefeller University have enhanced our understanding of the molecular basis of life — specifically the relationship between the structure and function of nucleic acids and proteins. They showed that DNA transfers genetic information and that the sugars ribose and deoxyribose are the key building blocks of the nucleic acids RNA and DNA.